Melatonin ameliorates cuprizone‐induced reduction of hippocampal neurogenesis, brain‐derived neurotrophic factor, and phosphorylation of cyclic AMP response element‐binding protein in the mouse dentate gyrus

Melatonin ameliorates cuprizone‐induced reduction of hippocampal neurogenesis, brain‐derived neurotrophic factor, and phosphorylation of cyclic AMP response element‐binding protein in the mouse dentate gyrus

Abstract Introduction The aim of this study was to investigate the effects of cuprizone on adult hippocampal neurogenesis in naïve mice. Additionally, we also studied how melatonin affects the neuronal degeneration induced by cuprizone. Methods Eight‐week‐old male C57BL/6J mice were randomly divided...

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Bibliographic Details
Main Authors: Woosuk Kim, Kyu Ri Hahn, Hyo Young Jung, Hyun Jung Kwon, Sung Min Nam, Jong Whi Kim, Joon Ha Park, Dae Young Yoo, Dae Won Kim, Moo‐Ho Won, Yeo Sung Yoon, In Koo Hwang
Format: Article
Language:English
Published: Wiley 2019-09-01
Series:Brain and Behavior
Subjects:
C57BL/6 mouse
cuprizone
hippocampus
melatonin
neurogenesis
Online Access:https://doi.org/10.1002/brb3.1388

Internet

https://doi.org/10.1002/brb3.1388

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