Antimicrobial Peptides with Enhanced Salt Resistance and Antiendotoxin Properties

Antimicrobial Peptides with Enhanced Salt Resistance and Antiendotoxin Properties

A strategy was described to design antimicrobial peptides (AMPs) with enhanced salt resistance and antiendotoxin activities by linking two helical AMPs with the Ala-Gly-Pro (AGP) hinge. Among the designed peptides, KR12AGPWR6 demonstrated the best antimicrobial activities even in high salt condition...

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Bibliographic Details
Main Authors: Hung-Lun Chu, Ya-Han Chih, Kuang-Li Peng, Chih-Lung Wu, Hui-Yuan Yu, Doris Cheng, Yu-Ting Chou, Jya-Wei Cheng
Format: Article
Language:English
Published: MDPI AG 2020-09-01
Series:International Journal of Molecular Sciences
Subjects:
antimicrobial peptide
salt resistance
lipopolysaccharide
antiendotoxin
cecropin-like
Online Access:https://www.mdpi.com/1422-0067/21/18/6810

Internet

https://www.mdpi.com/1422-0067/21/18/6810

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