Herpes Simplex Virus Type 1 Neuronal Infection Triggers the Disassembly of Key Structural Components of Dendritic Spines

Herpes Simplex Virus Type 1 Neuronal Infection Triggers the Disassembly of Key Structural Components of Dendritic Spines

Herpes simplex virus type 1 (HSV-1) is a widespread neurotropic virus. Primary infection of HSV-1 in facial epithelium leads to retrograde axonal transport to the central nervous system (CNS) where it establishes latency. Under stressful conditions, the virus reactivates, and new progeny are transpo...

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Bibliographic Details
Main Authors: Francisca Acuña-Hinrichsen, Adriana Covarrubias-Pinto, Yuta Ishizuka, María Francisca Stolzenbach, Carolina Martin, Paula Salazar, Maite A. Castro, Clive R. Bramham, Carola Otth
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Herpes Simplex Virus Type 1 (HSV-1)
neurodegeneration
neurotropic virus
Arc protein
memory consolidation
dendritic spines
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2021.580717/full

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https://www.frontiersin.org/articles/10.3389/fncel.2021.580717/full

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