Healthy Tissue Damage Following Cancer Ion Therapy: A Radiobiological Database Predicting Lymphocyte Chromosome Aberrations Based on the BIANCA Biophysical Model

Healthy Tissue Damage Following Cancer Ion Therapy: A Radiobiological Database Predicting Lymphocyte Chromosome Aberrations Based on the BIANCA Biophysical Model

Chromosome aberrations are widely considered among the best biomarkers of radiation health risk due to their relationship with late cancer incidence. In particular, aberrations in peripheral blood lymphocytes (PBL) can be regarded as indicators of hematologic toxicity, which is a major limiting fact...

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Bibliographic Details
Main Authors: Alessia Embriaco, Ricardo Ramos, Mario Carante, Alfredo Ferrari, Paola Sala, Valerio Vercesi, Francesca Ballarini
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
cancer
hadrontherapy
healthy tissue damage
chromosome aberrations
peripheral blood lymphocytes
biomarkers
Online Access:https://www.mdpi.com/1422-0067/22/19/10877

Internet

https://www.mdpi.com/1422-0067/22/19/10877

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