Loss of SPRY2 contributes to cancer-associated fibroblasts activation and promotes breast cancer development

Abstract The communication between tumor cells and tumor microenvironment plays a critical role in cancer development. Cancer-associated fibroblasts (CAFs) are the major components of the tumor microenvironment and take part in breast cancer formation and progression. Here, by comparing the gene exp...

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Bibliographic Details
Main Authors: Huijuan Dai, Wenting Xu, Lulu Wang, Xiao Li, Xiaonan Sheng, Lei Zhu, Ye Li, Xinrui Dong, Weihang Zhou, Chenyu Han, Yan Mao, Linli Yao
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Breast Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13058-023-01683-8