Anatomical, subset, and HIV-dependent expression of viral sensors and restriction factors

Summary: We developed viral sensor and restriction factor-cytometry by time of flight (VISOR-CyTOF), which profiles 19 viral sensors and restriction factors (VISORs) simultaneously in single cells, and applied it to 41 postmortem tissues from people with HIV. Mucosal myeloid cells are well equipped...

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Bibliographic Details
Main Authors: Ashley F. George, Jason Neidleman, Xiaoyu Luo, Julie Frouard, Natalie Elphick, Kailin Yin, Kyrlia C. Young, Tongcui Ma, Alicer K. Andrew, Ifeanyi J. Ezeonwumelu, Jesper G. Pedersen, Antoine Chaillon, Magali Porrachia, Brendon Woodworth, Martin R. Jakobsen, Reuben Thomas, Davey M. Smith, Sara Gianella, Nadia R. Roan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724015535