Fetal growth restriction followed by early catch-up growth impairs pancreatic islet morphology in male rats

Abstract Fetal growth restriction (FGR), followed by postnatal early catch-up growth, is associated with an increased risk of metabolic dysfunction, including type 2 diabetes in humans. This study aims to determine the effects of FGR and early catch-up growth after birth on the pathogenesis of type...

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Bibliographic Details
Main Authors: Mahboba Jabary, Atsuto Onoda, Yuma Kitase, Kazuto Ueda, Haruka Mimatsu, Shoji Go, Ryosuke Miura, Masahiro Tsuji, Yoshiyuki Takahashi, Masahiro Hayakawa, Yoshiaki Sato
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-28584-2