Increased expression of IDO1 is associated with improved survival and increased number of TILs in patients with high-grade serous ovarian cancer

Increased expression of IDO1 is associated with improved survival and increased number of TILs in patients with high-grade serous ovarian cancer

Background: The enzyme indoleamine 2,3-dioxygenase 1 (IDO1) plays a crucial role in regulating the immune system's response to tumors, but its exact role in cancer, especially in high-grade serous ovarian cancer (HGSOC), remains controversial. We aimed to investigate the prognostic impact of ID...

Full description

Bibliographic Details
Main Authors: Inga Hoffmann, Mihnea P. Dragomir, Nanna Monjé, Carlotta Keunecke, Catarina Alisa Kunze, Simon Schallenberg, Sofya Marchenko, Wolfgang D. Schmitt, Hagen Kulbe, Jalid Sehouli, Ioana Elena Braicu, Paul Jank, Carsten Denkert, Silvia Darb-Esfahani, David Horst, Bruno V. Sinn, Christine Sers, Philip Bischoff, Eliane T. Taube
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
HGSOC
TILs
IDO1
Ovarian cancer
Prognostic marker
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558623000581

Internet

http://www.sciencedirect.com/science/article/pii/S1476558623000581

Similar Items