The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor
<p>Abstract</p> <p>Background</p> <p>Huntington's disease (HD) pathogenesis is due to an expanded polyglutamine tract in huntingtin, but the specificity of neuronal loss compared with other polyglutamine disorders also implies a role for the protein's unknown...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2002-10-01
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Series: | BMC Neuroscience |
Online Access: | http://www.biomedcentral.com/1471-2202/3/15 |