Serum neurofilament light levels in normal aging and their association with morphologic brain changes

Neurofilament (NfL) levels in CSF and blood have been established as a biomarker of neuronal damage in neurodegenerative diseases, and there is an age-dependent increase in NfL levels in CSF. Here the authors demonstrate that serum NfL levels increase in healthy aging people and predict and correlat...

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Detaylı Bibliyografya
Asıl Yazarlar: Michael Khalil, Lukas Pirpamer, Edith Hofer, Margarete M. Voortman, Christian Barro, David Leppert, Pascal Benkert, Stefan Ropele, Christian Enzinger, Franz Fazekas, Reinhold Schmidt, Jens Kuhle
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Nature Portfolio 2020-02-01
Seri Bilgileri:Nature Communications
Online Erişim:https://doi.org/10.1038/s41467-020-14612-6