"Janus" cyclic peptides: a new approach to amyloid fibril inhibition?

Cyclic peptides are increasingly being shown as powerful inhibitors of fibril formation, and have the potential to be therapeutic agents for combating many debilitating amyloid-related diseases. One such example is a cyclic peptide derivative from the human apolipoprotein C-II, which has the ability...

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Bibliographic Details
Main Authors: Nevena Todorova, Levi Yeung, Andrew Hung, Irene Yarovsky
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3577749?pdf=render