Overexpression of Toll-like receptor 4 contributes to the internalization and elimination of Escherichia coli in sheep by enhancing caveolae-dependent endocytosis

Overexpression of Toll-like receptor 4 contributes to the internalization and elimination of Escherichia coli in sheep by enhancing caveolae-dependent endocytosis

Abstract Background Gram-negative bacterial infections have a major economic impact on both the livestock industry and public health. Toll-like receptor 4 (TLR4) plays a crucial role in host defence against Gram-negative bacteria. Exploring the defence mechanism regulated by TLR4 may provide new tar...

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Bibliographic Details
Main Authors: Yao Li, Yue Zhao, Xueling Xu, Rui Zhang, Jinlong Zhang, Xiaosheng Zhang, Yan Li, Shoulong Deng, Zhengxing Lian
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Animal Science and Biotechnology
Subjects:
Caveolae-dependent endocytosis
Host defence infection
Inflammatory responses
Monocytes
Toll-like receptor 4
Online Access:https://doi.org/10.1186/s40104-021-00585-z

Internet

https://doi.org/10.1186/s40104-021-00585-z

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