Single-gene knockout-coupled omics analysis identifies C9orf85 and CXorf38 as two uncharacterized human proteins associated with ZIP8 malfunction

Single-gene knockout-coupled omics analysis identifies C9orf85 and CXorf38 as two uncharacterized human proteins associated with ZIP8 malfunction

Human transmembrane protein metal cation symporter ZIP8 (SLC39A8) is a member of the solute carrier gene family responsible for intracellular transportation of essential micronutrients, including manganese, selenium, and zinc. Previously, we established a ZIP8-knockout (KO) human cell model using th...

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Bibliographic Details
Main Authors: Heng Wee Tan, Yan-Ming Xu, Zhan-Ling Liang, Na-Li Cai, Yu-Yao Wu, Andy T. Y. Lau
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
C9orf85
CXorf38
iTRAQ
proteomics
ZIP8
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2022.991308/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2022.991308/full

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