SERTAD1 Sensitizes Breast Cancer Cells to Doxorubicin and Promotes Lysosomal Protein Biosynthesis

SERTAD1 Sensitizes Breast Cancer Cells to Doxorubicin and Promotes Lysosomal Protein Biosynthesis

Acquired chemoresistance of tumor cells is an unwanted consequence of cancer treatment. Overcoming chemoresistance is particularly important for efficiently improving cancer therapies. Here, using multiple lines of evidence, we report the suppressive role of SERTAD1 in apoptosis/anoikis. Among vario...

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Bibliographic Details
Main Authors: Hai Anh Nguyen, Son Hai Vu, Samil Jung, Beom Suk Lee, Thi Ngoc Quynh Nguyen, Hyojeong Lee, Hye-gyeong Lee, Davaajargal Myagmarjav, Taeyeon Jo, Yeongseon Choi, Myeong-Sok Lee
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
breast cancer
anti-cancer drugs
anoikis
autophagy
SERTAD1
lysosomal biogenesis
Online Access:https://www.mdpi.com/2227-9059/10/5/1148

Internet

https://www.mdpi.com/2227-9059/10/5/1148

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