Precision oncology with selective RET inhibitor selpercatinib in -rearranged cancers
Rearranged during transfection ( RET ) is a protooncogene that encodes for receptor tyrosine kinase with downstream effects on multiple cellular pathways. Activating RET alterations can occur and lead to uncontrolled cellular proliferation as a hallmark of cancer development. Oncogenic RET fusions a...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
SAGE Publishing
2023-06-01
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Series: | Therapeutic Advances in Medical Oncology |
Online Access: | https://doi.org/10.1177/17588359231177015 |