Design of the STRIVE-IPF trial- study of therapeutic plasma exchange, rituximab, and intravenous immunoglobulin for acute exacerbations of idiopathic pulmonary fibrosis

Design of the STRIVE-IPF trial- study of therapeutic plasma exchange, rituximab, and intravenous immunoglobulin for acute exacerbations of idiopathic pulmonary fibrosis

Abstract Background Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF) affect a significant proportion of patients with IPF. There are limited data to inform therapeutic strategies for AE-IPF, despite its high mortality. We discuss the rationale and design of STRIVE-IPF, a randomized, mul...

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Bibliographic Details
Main Authors: Tejaswini Kulkarni, Gerard J. Criner, Daniel J. Kass, Ivan O. Rosas, Mary Beth Scholand, Daniel F. Dilling, Ross Summer, Steven R. Duncan
Format: Article
Language:English
Published: BMC 2024-03-01
Series:BMC Pulmonary Medicine
Subjects:
Idiopathic pulmonary fibrosis
Acute exacerbation of idiopathic pulmonary fibrosis
Autoantibody reduction
Clinical trial
Protocol
Online Access:https://doi.org/10.1186/s12890-024-02957-3

Internet

https://doi.org/10.1186/s12890-024-02957-3

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