K‐29 linked ubiquitination of Arrdc4 regulates its function in extracellular vesicle biogenesis

Abstract Extracellular vesicles (EVs) are important mediators of intercellular communication. However, EV biogenesis remains poorly understood. We previously defined a role for Arrdc4 (Arrestin domain containing protein 4), an adaptor for Nedd4 family ubiquitin ligases, in the biogenesis of EVs. Her...

Full description

Bibliographic Details
Main Authors: Ammara Usman Farooq, Kelly Gembus, Jarrod J. Sandow, Andrew Webb, Suresh Mathivanan, Jantina A. Manning, Sonia S. Shah, Natalie J. Foot, Sharad Kumar
Format: Article
Language:English
Published: Wiley 2022-02-01
Series:Journal of Extracellular Vesicles
Subjects:
Online Access:https://doi.org/10.1002/jev2.12188