Function of the active site lysine autoacetylation in Tip60 catalysis.
The 60-kDa HIV-Tat interactive protein (Tip60) is a key member of the MYST family of histone acetyltransferases (HATs) that plays critical roles in multiple cellular processes. We report here that Tip60 undergoes autoacetylation at several lysine residues, including a key lysine residue (i.e. Lys-32...
| मुख्य लेखकों: | , , |
|---|---|
| स्वरूप: | लेख |
| भाषा: | English |
| प्रकाशित: |
Public Library of Science (PLoS)
2012-01-01
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| श्रृंखला: | PLoS ONE |
| ऑनलाइन पहुंच: | http://europepmc.org/articles/PMC3314657?pdf=render |