Effect of body tissue composition on the outcome of patients with metastatic non-small cell lung cancer treated with PD-1/PD-L1 inhibitors.

Obesity and sarcopenia have been reported to affect outcomes in patients with non-small cell lung cancer (NSCLC) treated with immune checkpoint inhibitors (ICIs). We analyzed prospective data from 52 patients with non-oncogene driven metastatic NSCLC treated with ICIs. Body tissue composition was ca...

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Main Authors: Dimitrios Makrakis, Konstantinos Rounis, Alexandros-Pantelis Tsigkas, Alexandra Georgiou, Nikolaos Galanakis, George Tsakonas, Simon Ekman, Chara Papadaki, Alexia Monastirioti, Meropi Kontogianni, Ioannis Gioulbasanis, Dimitris Mavroudis, Sofia Agelaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0277708