Comparison of the inoculum effect of in vitro antibacterial activity of Imipenem/relebactam and Ceftazidime/avibactam against ESBL-, KPC- and AmpC-producing Escherichia coli and Klebsiella pneumoniae

Comparison of the inoculum effect of in vitro antibacterial activity of Imipenem/relebactam and Ceftazidime/avibactam against ESBL-, KPC- and AmpC-producing Escherichia coli and Klebsiella pneumoniae

Abstract Objective To evaluate effect of inoculum size of extended-spectrum β-Lactamase (ESBL)-producing-, AmpC-producing-, and KPC-producing Escherichia coli and Klebsiella pneumoniae on the in vitro antibacterial effects of imipenem/relebactam (IMR) and ceftazidime/avibactam (CZA). Methods We comp...

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Bibliographic Details
Main Authors: Xueting Wang, Luying Xiong, Yuan Wang, Kai Yang, Tingting Xiao, Xiaohui Chi, Tao Chen, Yanzi Zhou, Ping Lu, Dilimulati Dilinuer, Pin Shen, Yunbo Chen, Yonghong Xiao
Format: Article
Language:English
Published: BMC 2023-12-01
Series:Annals of Clinical Microbiology and Antimicrobials
Subjects:
Imipenem/relebactam
Ceftazidime/avibactam
Inoculum effect
ESBL
KPC
AmpC
Online Access:https://doi.org/10.1186/s12941-023-00660-5

Internet

https://doi.org/10.1186/s12941-023-00660-5

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