Comprehensive evaluation of the mechanism of human adipose mesenchymal stem cells ameliorating liver fibrosis by transcriptomics and metabolomics analysis

Abstract Liver fibrosis is a chronic liver disease with progressive wound healing reaction caused by liver injury. Currently, there is no FDA approved drugs for liver fibrosis. Human adipose mesenchymal stem cells (hADSCs) have shown remarkable therapeutic effects in liver diseases. However, few stu...

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Bibliographic Details
Main Authors: Guibao Ji, Zilong Zhang, Xinze Wang, Qiuxia Guo, Erlei Zhang, Chuanjiang Li
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-70281-1