Using fiber tractography and diffusion kurtosis imaging to evaluate neuroimaging changes in patients with cerebrotendinous xanthomatosis after stopping chenodeoxycholic acid treatment for three years

Using fiber tractography and diffusion kurtosis imaging to evaluate neuroimaging changes in patients with cerebrotendinous xanthomatosis after stopping chenodeoxycholic acid treatment for three years

Background: The aim of this study was to use tractography and diffusion kurtosis imaging (DKI) to evaluate cerebral white matter (WM) changes in patients with cerebrotendinous xanthomatosis (CTX) after stopping chenodeoxycholic acid (CDCA) treatment. Methods: Two siblings with CTX aged 40 and 38 yea...

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Bibliographic Details
Main Authors: Jun-Jun Lee, Chiung-Chih Chang, Wen-Neng Chang
Format: Article
Language:English
Published: Elsevier 2022-10-01
Series:Biomedical Journal
Subjects:
Cerebrotendinous xanthomatosis
Chenodeoxycholic acid
Magnetic resonance imaging
Tractography
Diffusion kurtosis imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S2319417021001153

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http://www.sciencedirect.com/science/article/pii/S2319417021001153

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