Peficitinib Inhibits the Chemotactic Activity of Monocytes via Proinflammatory Cytokine Production in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

Peficitinib Inhibits the Chemotactic Activity of Monocytes via Proinflammatory Cytokine Production in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

<b>Background:</b> This study was performed to examine the effects of the Janus kinase (JAK) inhibitor peficitinib on fibroblast-like synoviocytes (FLS) obtained from patients with rheumatoid arthritis (RA). <b>Methods:</b> To examine the expression of JAK1, JAK2, and JAK3 in...

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Bibliographic Details
Main Authors: Yuzo Ikari, Takeo Isozaki, Yumi Tsubokura, Tsuyoshi Kasama
Format: Article
Language:English
Published: MDPI AG 2019-06-01
Series:Cells
Subjects:
peficitinib
rheumatoid arthritis
fibroblast-like synoviocytes
monocyte chemotaxis
Online Access:https://www.mdpi.com/2073-4409/8/6/561

Internet

https://www.mdpi.com/2073-4409/8/6/561

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