Meiotic Chromosome Synapsis and XY-Body Formation In Vitro

To achieve spermatogenesis in vitro, one of the most challenging processes to mimic is meiosis. Meiotic problems, like incomplete synapsis of the homologous chromosomes, or impaired homologous recombination, can cause failure of crossover formation and subsequent chromosome nondisjunction, eventuall...

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Bibliographic Details
Main Authors: Qijing Lei, Eden Zhang, Ans M. M. van Pelt, Geert Hamer
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.761249/full