O-GlcNAc: A Sweetheart of the Cell Cycle and DNA Damage Response

The addition and removal of O-linked N-acetylglucosamine (O-GlcNAc) to and from the Ser and Thr residues of proteins is an emerging post-translational modification. Unlike phosphorylation, which requires a legion of kinases and phosphatases, O-GlcNAc is catalyzed by the sole enzyme in mammals, O-Glc...

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Bibliographic Details
Main Authors: Caifei Liu, Jing Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2018.00415/full