Oligodeoxynucleotides containing CpG motifs upregulate bactericidal activities of heterophils and enhance immunoprotection of neonatal broiler chickens against Salmonella Typhimurium septicemia

Oligodeoxynucleotides containing CpG motifs upregulate bactericidal activities of heterophils and enhance immunoprotection of neonatal broiler chickens against Salmonella Typhimurium septicemia

ABSTRACT: In the past, we demonstrated that oligodeoxynucleotides containing CpG motifs (CpG-ODN) mimicking bacterial DNA, stimulate the innate immune system of neonatal broiler chickens and protect them against Escherichia coli and Salmonella Typhimurium (S. Typhimurium) septicemia. The first line...

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Bibliographic Details
Main Authors: Iresha Subhasinghe, Ayumi Matsuyama-Kato, Khawaja Ashfaque Ahmed, Lisanework E. Ayalew, Hemlata Gautam, Shelly Popowich, Betty Chow-Lockerbie, Suresh K. Tikoo, Philip Griebel, Susantha Gomis
Format: Article
Language:English
Published: Elsevier 2024-10-01
Series:Poultry Science
Subjects:
neonatal broiler chicken
CpG-ODN
antibacterial immunity
innate immunity
Salmonella Typhimurium
Online Access:http://www.sciencedirect.com/science/article/pii/S0032579124006576

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http://www.sciencedirect.com/science/article/pii/S0032579124006576

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