Oligodeoxynucleotides containing CpG motifs upregulate bactericidal activities of heterophils and enhance immunoprotection of neonatal broiler chickens against Salmonella Typhimurium septicemia

Oligodeoxynucleotides containing CpG motifs upregulate bactericidal activities of heterophils and enhance immunoprotection of neonatal broiler chickens against Salmonella Typhimurium septicemia

ABSTRACT: In the past, we demonstrated that oligodeoxynucleotides containing CpG motifs (CpG-ODN) mimicking bacterial DNA, stimulate the innate immune system of neonatal broiler chickens and protect them against Escherichia coli and Salmonella Typhimurium (S. Typhimurium) septicemia. The first line...

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Detalles Bibliográficos
Autores principales: Iresha Subhasinghe, Ayumi Matsuyama-Kato, Khawaja Ashfaque Ahmed, Lisanework E. Ayalew, Hemlata Gautam, Shelly Popowich, Betty Chow-Lockerbie, Suresh K. Tikoo, Philip Griebel, Susantha Gomis
Formato: Artículo
Lenguaje:English
Publicado: Elsevier 2024-10-01
Colección:Poultry Science
Materias:
neonatal broiler chicken
CpG-ODN
antibacterial immunity
innate immunity
Salmonella Typhimurium
Acceso en línea:http://www.sciencedirect.com/science/article/pii/S0032579124006576

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