Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection.

Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection.

Secondary bacterial infections contribute to the excess morbidity and mortality of influenza A virus (IAV) infection. Disruption of lung integrity and impaired antibacterial immunity during IAV infection participate in colonization and dissemination of the bacteria out of the lungs. One key feature...

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Bibliographic Details
Main Authors: Ranin Beshara, Valentin Sencio, Daphnée Soulard, Adeline Barthélémy, Josette Fontaine, Thibault Pinteau, Lucie Deruyter, Mohamad Bachar Ismail, Christophe Paget, Jean-Claude Sirard, François Trottein, Christelle Faveeuw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-10-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007360

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https://doi.org/10.1371/journal.ppat.1007360

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