Impact of C4, C4A and C4B gene copy number variation in the susceptibility, phenotype and progression of systemic lupus erythematosus

Impact of C4, C4A and C4B gene copy number variation in the susceptibility, phenotype and progression of systemic lupus erythematosus

Abstract Background Complement component 4 (C4) gene copy number (GCN) affects the susceptibility to systemic lupus erythematosus (SLE) in different populations, however the possible phenotype significance remains to be determined. This study aimed to associate C4A, C4B and total C4 GCN and SLE, foc...

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Bibliographic Details
Main Authors: Kaline Medeiros Costa Pereira, Sandro Perazzio, Atila Granado A. Faria, Eloisa Sa Moreira, Viviane C. Santos, Marcelle Grecco, Neusa Pereira da Silva, Luis Eduardo Coelho Andrade
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Advances in Rheumatology
Subjects:
Complement C4
C4A
C4B
Gene copy number variation
Systemic lupus erythematosus
Online Access:http://link.springer.com/article/10.1186/s42358-019-0076-6

Internet

http://link.springer.com/article/10.1186/s42358-019-0076-6

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