Tumor-infiltrating lymphocyte enrichment predicted by CT radiomics analysis is associated with clinical outcomes of non-small cell lung cancer patients receiving immune checkpoint inhibitors

Tumor-infiltrating lymphocyte enrichment predicted by CT radiomics analysis is associated with clinical outcomes of non-small cell lung cancer patients receiving immune checkpoint inhibitors

BackgroundEnrichment of tumor-infiltrating lymphocytes (TIL) in the tumor microenvironment (TME) is a reliable biomarker of immune checkpoint inhibitors (ICI) in non-small cell lung cancer (NSCLC). Phenotyping through computed tomography (CT) radiomics has the overcome the limitations of tissue-base...

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Bibliographic Details
Main Authors: Changhee Park, Dong Young Jeong, Yeonu Choi, You Jin Oh, Jonghoon Kim, Jeongun Ryu, Kyunghyun Paeng, Se-Hoon Lee, Chan-Young Ock, Ho Yun Lee
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
radiomics
immune checkpoint inhibitor (ICI)
immunotherapy
tumor infiltrating lymphocyte (TIL)
artificial intelligence
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1038089/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1038089/full

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