XJB-5-131 protects chondrocytes from ferroptosis to alleviate osteoarthritis progression via restoring Pebp1 expression

XJB-5-131 protects chondrocytes from ferroptosis to alleviate osteoarthritis progression via restoring Pebp1 expression

Background: Osteoarthritis (OA) is the most common age-related musculoskeletal disease. However, there is still a lack of therapy that can modify OA progression due to the complex pathogenic mechanisms. The aim of the study was to explore the role and mechanism of XJB-5-131 inhibiting chondrocytes f...

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Bibliographic Details
Main Authors: Wei Sun, Zhongyang Lv, Weitong Li, Jun Lu, Ya Xie, Peng Wang, Ruiyang Jiang, Jian Dong, Hu Guo, Zizheng Liu, Yuxiang Fei, Guihua Tan, Maochun Wang, Kewei Ren, Jun Xu, Huiqing Sun, Xuefeng Jiang, Dongquan Shi
Format: Article
Language:English
Published: Elsevier 2024-01-01
Series:Journal of Orthopaedic Translation
Subjects:
Cartilage degeneration
Ferroptosis
Osteoarthritis
XJB-5-131
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X23001067

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http://www.sciencedirect.com/science/article/pii/S2214031X23001067

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