Targeting the RNA m6A modification for cancer immunotherapy

Targeting the RNA m6A modification for cancer immunotherapy

Abstract N 6-methyladenosine (m6A) is the most abundant epigenetic modification of RNA, and its dysregulation drives aberrant transcription and translation programs that promote cancer occurrence and progression. Although defective gene regulation resulting from m6A often affects oncogenic and tumor...

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Bibliographic Details
Main Authors: Xinxin Li, Shoubao Ma, Youcai Deng, Ping Yi, Jianhua Yu
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Molecular Cancer
Subjects:
Tumor microenvironment
Cancer immunotherapy
Epigenetics
N 6-methyladenosine
m6A modification
m6A regulators
Online Access:https://doi.org/10.1186/s12943-022-01558-0

Internet

https://doi.org/10.1186/s12943-022-01558-0

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