C/EBP-beta regulates endoplasmic reticulum stress-triggered cell death in mouse and human models.

Endoplasmic reticulum (ER) stress elicits the unfolded protein response (UPR), initially aimed at coping with the stress, but triggering cell death upon further stress. ER stress induces the C/EBP-beta variant Liver-enriched Activating Protein (LAP), followed by the dominant-negative variant, Liver...

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Bibliographic Details
Main Authors: Ofir Meir, Efrat Dvash, Ariel Werman, Menachem Rubinstein
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-03-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2831074?pdf=render