Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory

Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory

For some inducible genes, the rate and molecular mechanism of transcriptional activation depend on the prior experiences of the cell. This phenomenon, called epigenetic transcriptional memory, accelerates reactivation, and requires both changes in chromatin structure and recruitment of poised RNA po...

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Bibliographic Details
Main Authors: Bethany Sump, Donna G Brickner, Agustina D'Urso, Seo Hyun Kim, Jason H Brickner
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-05-01
Series:eLife
Subjects:
epigenetics
chromatin
nuclear pore
fitness
mitosis
transcriptional memory
Online Access:https://elifesciences.org/articles/77646

Internet

https://elifesciences.org/articles/77646

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