Improved Tissue-Based Analytical Test Methods for Orellanine, a Biomarker of Cortinarius Mushroom Intoxication

Improved Tissue-Based Analytical Test Methods for Orellanine, a Biomarker of Cortinarius Mushroom Intoxication

Orellanine (OR) toxin is produced by mushrooms of the genus Cortinarius which grow in North America and in Europe. OR poisoning is characterized by severe oliguric acute renal failure, with a mortality rate of 10%–30%. Diagnosis of OR poisoning currently hinges on a history of ingestion of Cortinari...

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Bibliographic Details
Main Authors: Poojya Anantharam, Dahai Shao, Paula M. Imerman, Eric Burrough, Dwayne Schrunk, Tsevelmaa Sedkhuu, Shusheng Tang, Wilson Rumbeiha
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Toxins
Subjects:
orellanine
Cortinarius mushrooms
renal failure
analytical method
diagnosis
liver injury
HPLC
LC-MS/MS
Online Access:http://www.mdpi.com/2072-6651/8/5/158

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http://www.mdpi.com/2072-6651/8/5/158

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