The Ferrous Iron-Responsive BqsRS Two-Component System Activates Genes That Promote Cationic Stress Tolerance

ABSTRACT The physiological resistance of pathogens to antimicrobial treatment is a severe problem in the context of chronic infections. For example, the mucus-filled lungs of cystic fibrosis (CF) patients are readily colonized by diverse antibiotic-resistant microorganisms, including Pseudomonas aer...

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Bibliographic Details
Main Authors: Naomi N. Kreamer, Flavia Costa, Dianne K. Newman
Format: Article
Language:English
Published: American Society for Microbiology 2015-05-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.02549-14