A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody

A combination of two resistance mechanisms is critical for tick-borne encephalitis virus escape from a broadly neutralizing human antibody

Summary: Tick-borne encephalitis virus (TBEV) is a flavivirus that causes human neuroinfections and represents a growing health problem. The human monoclonal antibody T025 targets envelope protein domain III (EDIII) of TBEV and related tick-borne flaviviruses, potently neutralizing TBEV in vitro and...

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Bibliographic Details
Main Authors: Pavel Svoboda, Jan Haviernik, Petr Bednar, Milos Matkovic, Tomás Cervantes Rincón, Jennifer Keeffe, Martin Palus, Jiri Salat, Marianna Agudelo, Michel C. Nussenzweig, Andrea Cavalli, Davide F. Robbiani, Daniel Ruzek
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:Cell Reports
Subjects:
CP: Microbiology
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723011610

Internet

http://www.sciencedirect.com/science/article/pii/S2211124723011610

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