Fetal loss in pregnant rhesus macaques infected with high-dose African-lineage Zika virus.

Fetal loss in pregnant rhesus macaques infected with high-dose African-lineage Zika virus.

Countermeasures against Zika virus (ZIKV), including vaccines, are frequently tested in nonhuman primates (NHP). Macaque models are important for understanding how ZIKV infections impact human pregnancy due to similarities in placental development. The lack of consistent adverse pregnancy outcomes i...

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Bibliographic Details
Main Authors: Lauren E Raasch, Keisuke Yamamoto, Christina M Newman, Jenna R Rosinski, Phoenix M Shepherd, Elaina Razo, Chelsea M Crooks, Mason I Bliss, Meghan E Breitbach, Emily L Sneed, Andrea M Weiler, Xiankun Zeng, Kevin K Noguchi, Terry K Morgan, Nicole A Fuhler, Ellie K Bohm, Alexandra J Alberts, Samantha J Havlicek, Sabrina Kabakov, Ann M Mitzey, Kathleen M Antony, Karla K Ausderau, Andres Mejia, Puja Basu, Heather A Simmons, Jens C Eickhoff, Matthew T Aliota, Emma L Mohr, Thomas C Friedrich, Thaddeus G Golos, David H O'Connor, Dawn M Dudley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-08-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0010623

Internet

https://doi.org/10.1371/journal.pntd.0010623

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