Regional variations in growth plate chondrocyte deformation as predicted by three-dimensional multi-scale simulations.

The physis, or growth plate, is a complex disc-shaped cartilage structure that is responsible for longitudinal bone growth. In this study, a multi-scale computational approach was undertaken to better understand how physiological loads are experienced by chondrocytes embedded inside chondrons when s...

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Bibliographic Details
Main Authors: Jie Gao, Esra Roan, John L Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4401775?pdf=render