PTBP1 is required for embryonic development before gastrulation.

Polypyrimidine-tract binding protein 1 (PTBP1) is an important cellular regulator of messenger RNAs influencing the alternative splicing profile of a cell as well as its mRNA stability, location and translation. In addition, it is diverted by some viruses to facilitate their replication. Here, we us...

Full description

Bibliographic Details
Main Authors: Jakob Suckale, Olivia Wendling, Jimmy Masjkur, Melanie Jäger, Carla Münster, Konstantinos Anastassiadis, A Francis Stewart, Michele Solimena
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21423341/pdf/?tool=EBI