The Fused Methionine Sulfoxide Reductase MsrAB Promotes Oxidative Stress Defense and Bacterial Virulence in Fusobacterium nucleatum

The Fused Methionine Sulfoxide Reductase MsrAB Promotes Oxidative Stress Defense and Bacterial Virulence in Fusobacterium nucleatum

ABSTRACT Fusobacterium nucleatum, an anaerobic Gram-negative bacterium frequently found in the human oral cavity and some extra-oral sites, is implicated in several important diseases: periodontitis, adverse pregnancy outcomes, and colorectal cancer. To date, how this obligate anaerobe copes with ox...

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Bibliographic Details
Main Authors: Matthew Scheible, Cuong T. Nguyen, Truc Thanh Luong, Ju Huck Lee, Yi-Wei Chen, Chungyu Chang, Manuel Wittchen, Martha I. Camacho, Bethany L. Tiner, Chenggang Wu, Andreas Tauch, Asis Das, Hung Ton-That
Format: Article
Language:English
Published: American Society for Microbiology 2022-06-01
Series:mBio
Subjects:
Fusobacterium nucleatum
MsrAB
adherence
cell invasion
gene regulation
oxidative stress
Online Access:https://journals.asm.org/doi/10.1128/mbio.03022-21

Internet

https://journals.asm.org/doi/10.1128/mbio.03022-21

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