Regulation of 4-HNE via SMARCA4 Is Associated with Worse Clinical Outcomes in Hepatocellular Carcinoma

Regulation of 4-HNE via SMARCA4 Is Associated with Worse Clinical Outcomes in Hepatocellular Carcinoma

Accumulation of 4-hydroxynonenal (4-HNE), a marker of lipid peroxidation, has various favorable and unfavorable effects on cancer cells; however, the clinicopathological significance of its accumulation in hepatocellular carcinoma (HCC) and its metabolic pathway remain unknown. This study analyzed 4...

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Bibliographic Details
Main Authors: Shiori Watabe, Yukari Aruga, Ryoko Kato, Genji Kawade, Yuki Kubo, Anna Tatsuzawa, Iichiroh Onishi, Yuko Kinowaki, Sachiko Ishibashi, Masumi Ikeda, Yuki Fukawa, Keiichi Akahoshi, Minoru Tanabe, Morito Kurata, Kenichi Ohashi, Masanobu Kitagawa, Kouhei Yamamoto
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomedicines
Subjects:
4-HNE
SMARCA4
hepatocellular carcinoma
lipid peroxidation
antioxidant enzyme
Online Access:https://www.mdpi.com/2227-9059/11/8/2278

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https://www.mdpi.com/2227-9059/11/8/2278

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