Effects of subconjunctival administration of anti-high mobility group box 1 on dry eye in a mouse model of Sjӧgren's syndrome.

Effects of subconjunctival administration of anti-high mobility group box 1 on dry eye in a mouse model of Sjӧgren's syndrome.

Extracellular high mobility group box 1 (HMGB1) acts as a damage associated molecular pattern molecule through the Toll-like receptor to promote autoreactive B cell activation, which may be involved in the pathogenesis of Sjӧgren's syndrome. The aim of this study was to investigate the effect o...

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Bibliographic Details
Main Authors: Kyeong Hwan Kim, Dong Hyun Kim, Hyun Jeong Jeong, Jin Suk Ryu, Yu Jeong Kim, Joo Youn Oh, Mee Kum Kim, Won Ryang Wee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5570279?pdf=render

Internet

http://europepmc.org/articles/PMC5570279?pdf=render

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