Dieting alleviates hyperuricemia and organ injuries in uricase-deficient rats via down-regulating cell cycle pathway

Dieting is a basic treatment for lowering hyperuricemia. Here, we aimed to determine the optimal amount of dietary food that lowers serum uric acid (SUA) without modifying the dietary ingredients in rats. Increased SUA was found in food-deprived 45-day-old uricase-deficient rats (Kunming-DY rats), a...

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Bibliographic Details
Main Authors: Yun Yu, Xulian Wan, Dan Li, Yalin Qi, Ning Li, Guangyun Luo, Hua Yin, Lei Wang, Wan Qin, Yongkun Li, Lvyu Li, Weigang Duan
Format: Article
Language:English
Published: PeerJ Inc. 2023-09-01
Series:PeerJ
Subjects:
Online Access:https://peerj.com/articles/15999.pdf