Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm

Quantification of the pace of biological aging in humans through a blood test, the DunedinPoAm DNA methylation algorithm

Biological aging is the gradual, progressive decline in system integrity that occurs with advancing chronological age, causing morbidity and disability. Measurements of the pace of aging are needed as surrogate endpoints in trials of therapies designed to prevent disease by slowing biological aging....

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Bibliographic Details
Main Authors: Daniel W Belsky, Avshalom Caspi, Louise Arseneault, Andrea Baccarelli, David L Corcoran, Xu Gao, Eiliss Hannon, Hona Lee Harrington, Line JH Rasmussen, Renate Houts, Kim Huffman, William E Kraus, Dayoon Kwon, Jonathan Mill, Carl F Pieper, Joseph A Prinz, Richie Poulton, Joel Schwartz, Karen Sugden, Pantel Vokonas, Benjamin S Williams, Terrie E Moffitt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-05-01
Series:eLife
Subjects:
aging
biological aging
DNA methylation
epigenetic
human
life-course
Online Access:https://elifesciences.org/articles/54870

Internet

https://elifesciences.org/articles/54870

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