Effect of the sequence data deluge on the performance of methods for detecting protein functional residues

Effect of the sequence data deluge on the performance of methods for detecting protein functional residues

Abstract Background The exponential accumulation of new sequences in public databases is expected to improve the performance of all the approaches for predicting protein structural and functional features. Nevertheless, this was never assessed or quantified for some widely used methodologies, such a...

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Bibliographic Details
Main Authors: Diego Garrido-Martín, Florencio Pazos
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Bioinformatics
Subjects:
Sequence database
Functional residue
Conserved positions
Family-dependent conserved position
Specificity-determining position
Functional subfamily
Online Access:http://link.springer.com/article/10.1186/s12859-018-2084-7

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http://link.springer.com/article/10.1186/s12859-018-2084-7

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