Amphibian (Xenopus laevis) Interleukin-8 (CXCL8): A Perspective on the Evolutionary Divergence of Granulocyte Chemotaxis

Amphibian (Xenopus laevis) Interleukin-8 (CXCL8): A Perspective on the Evolutionary Divergence of Granulocyte Chemotaxis

The glutamic acid-leucine-arginine (ELR) motif is a hallmark feature shared by mammalian inflammatory CXC chemokines such the granulocyte chemo-attractant CXCL8 (interleukin-8, IL-8). By contrast, most teleost fish inflammatory chemokines lack this motif. Interestingly, the amphibian Xenopus laevis...

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Bibliographic Details
Main Authors: Daphne V. Koubourli, Amulya Yaparla, Milan Popovic, Leon Grayfer
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Immunology
Subjects:
interleukin-8
amphibian
granulocyte
chemotaxis
CXCL8
FV3
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02058/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02058/full

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