Amphibian (Xenopus laevis) Interleukin-8 (CXCL8): A Perspective on the Evolutionary Divergence of Granulocyte Chemotaxis

The glutamic acid-leucine-arginine (ELR) motif is a hallmark feature shared by mammalian inflammatory CXC chemokines such the granulocyte chemo-attractant CXCL8 (interleukin-8, IL-8). By contrast, most teleost fish inflammatory chemokines lack this motif. Interestingly, the amphibian Xenopus laevis...

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Hlavní autoři: Daphne V. Koubourli, Amulya Yaparla, Milan Popovic, Leon Grayfer
Médium: Článek
Jazyk:English
Vydáno: Frontiers Media S.A. 2018-09-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/article/10.3389/fimmu.2018.02058/full