Proof-of-Concept Method to Study Uncharacterized Methyltransferases Using PRDM15

The PRDM family of methyltransferases has been implicated in cellular proliferation and differentiation and is deregulated in human diseases, most notably in cancer. PRDMs are related to the SET domain family of methyltransferases; however, from the 19 PRDMs only a few PRDMs with defined enzymatic a...

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Bibliographic Details
Main Authors: Li-Na Zhao, Ernesto Guccione, Philipp Kaldis
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/2/1327