Senescent Kidney Cells in Hypertensive Patients Release Urinary Extracellular Vesicles

Background Hypertension may be associated with renal cellular injury. Cells in distress release extracellular vesicles (EVs), and their numbers in urine may reflect renal injury. Cellular senescence, an irreversible growth arrest in response to a noxious milieu, is characterized by release of proinf...

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Bibliographic Details
Main Authors: Adrian Santelli, In O. Sun, Alfonso Eirin, Abdelrhman M. Abumoawad, John R. Woollard, Amir Lerman, Stephen C. Textor, Amrutesh S. Puranik, Lilach O. Lerman
Format: Article
Language:English
Published: Wiley 2019-06-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.119.012584